Kasabach-Merritt syndrome associated with angiosarcoma of the scalp successfully treated with chemoradiotherapy.

Sir, Kasabach-Merritt syndrome (KMS) is a condition of consumption coagulopathy in patients bearing vascular tumours and malformations. KMS is seen not only in infants bearing large haemangiomas, but has also been observed in various vascular diseases, such as bluerubber-bleb nevus syndrome (1) and Osler-Weber-Rendu disease (2). Angiosarcoma is a rare malignancy of vascular or lymphatic endothelial cell origin. Angiosarcoma has a poor prognosis and association with KMS, usually seen at advanced stage, makes the patients’ clinical course worse (3). KMS with early stage angiosarcoma of the scalp has not been reported previously. We report here a case of a now 70-year-old patient with KMS associated with angiosarcoma of the scalp and disseminated intravascular coagulation, which was successfully controlled by anti-cancer treatment.